TIMP-1 (A, B), TIMP-3 (C, D), SLPI (E, F) and PAI-1 (G, H) scores were each higher in OA than in PM (A, C, E, G) and were each associated with greater chondropathy (B, D, F, H). A, C, E and G: box and whisker plots. *P < 0.05, **P < 0.01 for differences between PM and OA. B, D, F and H: scatter plots of data from patients with OA (○) and PM controls (▴).