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. 2010 Apr;18(4):563–571. doi: 10.1016/j.joca.2009.11.015

Table I.

Criteria for scoring immunoreactivity in articular cartilage

Score Criteria
TIMP-1 and TIMP-3 SLPI PAI-1 VEGF
0 No positive superficial chondrocytes No positive superficial chondrocytes No positive chondrocytes No positive superficial chondrocytes
1 Some, but fewer than 10% of superficial chondrocytes positive Fewer than 50% of superficial chondrocytes positive Positive chondrocytes in the superficial zone Positive chondrocytes in the superficial zone
2 Thin layer (up to three cells deep) of positive superficial chondrocytes 50% or more of the superficial chondrocytes positive Positive chondrocytes in the superficial and intermediate zones Positive chondrocytes in the superficial and intermediate zones
3 Thick layer (>3 cells deep) of positive superficial chondrocytes Positive chondrocytes in the superficial, intermediate and deep zones