Table 2.
Summary of pathological findings
| Diagnosis | Subject | Eyes | Retina |
Optic nerve |
Iris | ||
|---|---|---|---|---|---|---|---|
| Periphlebitis | Cell loss | Gliosis | Atrophy | Reaction | |||
| Acute multiple sclerosis | 6 | 9 | 0% | 55% | 50% | 50% | 55% |
| Chronic multiple sclerosis | 76 | 121 | 13% (P = 0.125) | 80% (P < 0.001) | 72% (P < 0.001) | 71% (P < 0.001) | 72% (P = 0.001) |
| Relapsing remitting multiple sclerosis | 8 | 15 | 14% | 100% | 83% | 73% | 71% |
| Secondary progressive multiple sclerosis | 51 | 84 | 15% | 79% | 71% | 55% | 75% |
| Primary progressive multiple sclerosis | 13 | 22 | 5% | 67% | 67% | 70% | 58% |
| Unable to classify | 2 | 2 | 0% | 100% | 100% | 100% | 100% |
| Other neurological disease | 10 | 16 | 0% | 19% | 8% | 13% | 25% |
| Total | 92 | 148 | 11% | 73% | 65% | 65% | 67% |
All percentages are for numbers of eyes (not subjects). All P-values are for multivariable logistic regression comparing chronic multiple sclerosis to patients with other neurological disease controlling for age and gender.