Figure 5. ROC curves of molecular risk score compared with clinical and histologic features.

(A) To assess the sensitivity and specificity of the molecular classifier compared with that of clinical features, we compared the ROC curve derived from the molecular risk score with variables significantly associated with graft loss in a multivariate analysis. AUC is indicated for each parameter. (B) Accuracy (total correct predictions/total samples) for varying risk score thresholds for predicting graft failure. The dashed line represents the accuracy when the presence of proteinuria was used as the single threshold for predicting failure. The dotted line is the accuracy when all samples are predicted to survive. ah, arteriolar hyalinosis.