Fig. 4.

Schematic illustration of phosphorylation events in central metabolic pathways of M. pneumoniae. Of the central metabolic pathways, only glycolysis is operative in M. pneumoniae, and a few carbon sources such as glucose, fructose, and glycerol can be utilized. Pyruvate can be oxidized to acetate or reduced to lactate. An incomplete pentose phosphate pathway serves to generate phosphoribosyl pyrophosphate for nucleotide biosynthesis. Phosphorylated enzymes are highlighted in gray. DHAP, dihydroxyacetone phosphate; GPC, glycerophosphorylcholine; PEP, phosphoenolpyruvate; PRPP, phosphoribosyl pyrophosphate; P, phosphate.