TABLE 1.

Impact of PM5-S on Na⁺-dependent and Na⁺-independent TC uptake in PHH

PHH were incubated with 1 μm TC (0.2 mm [³H]TC + 0.8 μm TC) for 20 min with/without 50 μm PM5-S in sodium/choline chloride-based uptake media. Values represent mean ± S.E. of n = 3.

Bile acid uptake component and treatment	Uptake (±S.E.)
	pmol/mg
Total untreated	67.3 ± 21.5
Total + 50 mm PM5-S	1.3 ± 0.7a
Na+-dependent untreated	64.2 ± 21.8
Na+-dependent + 50 mm PM5-S	1.0 ± 0.7a
Na+-independent untreated	3.1 ± 0.8
Na+-independent + 50 mm PM5-S	0.3 ± 0.2a

^a p < 0.05 for PM5-S-treated versus control untreated.