FIGURE 2.

Changes in Integrin β1D levels after viral expression of γ-SG. A, immunoblot of muscle lysates from untreated C57 and gsg^−/− mice, and from gsg^−/− mice injected with WTgsg or Y6Agsg. B, quantification of integrin β1D normalized to tubulin for n = 3 muscle lysates per condition. Integrin β1D increased by >2-fold in muscles from gsg^−/− mice compared with those from C57 mice. Expression of WTgsg or Y6Agsg in muscles of gsg^−/− resulted in a partial reduction of integrin β1D (Int β1D) such that there was no significant difference between treated muscles and C57 muscles or gsg^−/− muscles. Comparisons based on one-way ANOVA followed by Tukey's multiple comparison test.