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. Author manuscript; available in PMC: 2010 May 28.
Published in final edited form as: Circulation. 2008 May 27;117(21):2776–2784. doi: 10.1161/CIRCULATIONAHA.107.740878

TABLE 2.

Independent Predictors of Outcome after Diagnosis

Endpoints Independent Multivariate Predictors
Predictor HR CI p value
Medical Cardiovascular Events Cardiac Death, CHF, New CV Symptoms, Stroke, Endocarditis Age≥50 years 4.7 2.2-9.6 <0.01
Valve Degeneration 2.6 1.2-5.3 0.016
Surgical Cardiovascular Events Aortic Valve Surgery, Thoracic Aorta Surgery Age≥50 years 2.9 1.3-6.2 0.01
Valve Degeneration 4.5 2.1-9.3 <0.01
Aortic Valve Surgery Valvotomy or valve replacement Age≥50 years 4.8 2.0-11.6 <0.01
Valve Degeneration 6.9 3.0-15.5 <0.01
Aortic Aneurysm Surgery Baseline Aorta≥40 mm 10.8 1.8-77.3 <0.01
Total Events Medical or Surgical Events Age≥50 years 3.0 1.5-5.7 <0.01
Valve Degeneration 2.4 1.2-4.5 0.016

CHF: Congestive heart failure; CV: Cardiovascular