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. 2010 May 28;5(5):e10884. doi: 10.1371/journal.pone.0010884

Figure 10. VV morphogenesis is disrupted in the p85-deficient cells.

Figure 10

p85α−/−β−/− cells were infected with B5-GFP WR for 17 hours. A,B,C. p85α−/−β−/− cells exhibit characteristic virion morphogenesis (A,B. 4,100X, OsO4 Fix; C. 14,000X OsO4 fix), but are stuck at the IMV wrapping step. 1) Crescents; 2) Immature virions; 3) Mature virion, IMV (4,100X, OsO4 Fix). Note the lack of virus associated with the plasma membrane.