. 2010 May 28;5(5):e10884. doi: 10.1371/journal.pone.0010884

Table 1. 50% Inhibitory Concentration (IC₅₀) of PI3K inhibitors added post-adsorption to poxvirus-infected monolayers.

	Inhibits:	Vaccinia IC₅₀	Ectromelia IC₅₀	Monkeypox IC₅₀	Other Targets:
AS1	p110-gamma	37.4±1.1 µM	13.0±1.3 µM	12.1±3.9 µM	p110-alpha, p110-beta, p110-delta, PKCbII¹
AS2	p110-gamma	44.6±2.1 µM	44.7±14.2 µM	9.3±4.3 µM	p110-alpha, p110-beta, p110-delta¹
B0304	p110-alpha	9.8±0.3 µM	1.8±0 µM	6.1±4.8 µM	p110-beta, p110-delta, p110gamma²
LY294002	Broad-Spectrum PI3K Inhibitor³	44.1±6.9 µM	14.4±4.2 µM	20.3±10.7 µM

Table 1. 50% Inhibitory Concentration (IC50) of PI3K inhibitors added post-adsorption to poxvirus-infected monolayers.