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. 2010 May 28;5(5):e10891. doi: 10.1371/journal.pone.0010891

Figure 1. Paw incision-induced mechanical allodynia and increased glial marker expression spontaneously resolve.

Figure 1

(A) 50% paw withdrawal thresholds were evaluated in naïve animals and ipsilateral to paw incision in animals at days 1, 3 and 9 after surgery (n = 8 per group). *p<0.05 vs. baseline values by one-way ANOVA repeated measures followed by Dunnett's post test. #p<0.05 vs. postoperative day 1 values by one-way ANOVA repeated measures followed by Dunnett's post test. (B) L5 spinal cord sections were stained for Iba-1 (green) and GFAP (red). Representative confocal images show detail of the superficial laminae of the L5 dorsal horn in naïve animals and ipsilateral to paw incision in rats at days 1, 3 and 9 after surgery. BL: Baseline.