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. 2010 May 28;5(5):e10897. doi: 10.1371/journal.pone.0010897

Figure 2. IL-4 and IFN-γ secreting cells in response to inactivated influenza antigen.

Figure 2

The cellular immune responses were analyzed in splenocytes by ELISPOT for IL-4 and IFN-γ production 2 weeks after vaccination by re-stimulation with nucleoprotein (NP) and hemagglutinin (HA) class I (A,B) and class II (C,D) restricted peptides. Groups are as described in the legend of Table 1. Data are pooled from three independent experiments and are the average ± SEM for six mice per group. Statistical significance of the differences between groups in comparison was calculated by Student's test (p<0.05). Statistics; a: p<0.05 comparing all groups to the PR8 alone group, b: <0.05 comparing adjuvanted groups to PR8-CT group (PR8-CT-RA, PR8-CT-OA, PR8-OA-RA).