Table I.

Demographic and other characteristics of colon cancer patients and controls

	Number of cases	Number of controls	Adjusted ORa	95% CI
Race/ethnicity
Non-Hispanic White	544	570
Black	142	97
Hispanic	105	68
Asian	40	20
Age (years)
≤60	191	224
61–65	199	182
66–70	240	182
>70	201	167
Menopause type
Natural menopause	438	388	1.00
Complete hysterectomy	111	114	0.79	0.56–1.11
Simply hysterectomy	173	148	0.85	0.59–1.20
HT/other	92	93	1.10	0.78–1.57
Other	17	12	1.34	0.66–3.17
P (4 df)			0.38
Age at menopause (years)
<40	164	139	1.00
40–44	125	106	1.03	0.72–1.54
45–49	207	224	0.76	0.52–1.10
50–54	256	218	1.05	0.72–1.56
≥55	79	68	0.93	0.57–1.50
P trend			0.31
Age at menarche (years)
≤11	183	179	1.00
12	210	160	1.34	1.01–1.88
13	207	230	0.94	0.72–1.30
14	102	95	1.09	0.77–1.62
≥15	129	91	1.40	1.01–2.08
P trend			0.60
Number of births
0	106	94	1.00
1	104	95	0.82	0.54–1.26
2	226	204	0.91	0.64–1.32
3	177	165	0.79	0.54–1.15
4	98	101	0.66	0.44–1.03
5+	120	96	0.73	0.49–1.15
P trend			0.070
Family history of colorectal cancer
No	717	671	1.00
Yes	114	84	1.23	0.93–1.76
P (1 df)			0.15
OCs
Never	454	356	1.00
<5 years	243	222	1.04	0.79–1.34
5–10 years	54	82	0.64	0.43–0.97
>10 years	80	95	0.77	0.53–1.12
P trend			0.062
Use of aspirin
Never	551	460	1.00
≤2 years	110	80	1.14	0.80–1.56
>2–5 years	57	60	0.82	0.53–1.20
>5–14 years	47	83	0.42	0.28–0.63
>14 years	66	72	0.80	0.53–1.13
P trend			0.002
Physical activity (h/week)
Never	219	176	1.00
≤0.75	224	209	0.88	0.67–1.19
>0.75–1.5	99	117	0.73	0.52–1.06
>1.5–3	142	109	1.26	0.90–1.81
>3	147	144	1.00	0.74–1.43
P trend			0.58
Years of smoking
0	382	375	1.00
1–20	139	142	1.07	0.80–1.45
21–40	202	165	1.26	0.97–1.67
>40	108	73	1.49	1.02–2.12
P trend			0.033
Years of alcohol use
0	441	381	1.00
1–20	165	156	0.97	0.71–1.25
21–40	158	153	1.10	0.83–1.49
>40	67	65	0.85	0.59–1.29
P trend			0.89
Current BMI (kg/m2)
≤23.2	200	208	1.00
>23.2–26.2	193	191	1.11	0.81–1.47
>26.2–30.3	219	181	1.28	0.94–1.72
>30.3	219	175	1.27	0.92–1.71
P trend			0.18
Age 50 BMI (kg/m2)b
≤21.9	181	222	1.00
>21.9–24.2	185	190	1.38	1.02–1.87
>24.2–27.4	225	187	1.68	1.24–2.28
>27.4	240	156	2.34	1.69–3.26
P trend			<0.001
Age 60 BMI (kg/m2)b
≤22.8	147	169	1.00
>22.8–25.5	170	158	1.33	0.95–1.85
>25.5–28.9	172	138	1.61	1.14–2.28
>28.9	190	127	1.87	1.30–2.69
P trend			0.002

^aORs were adjusted for age (≤60, 61–65, 66–70 and >70 years), race/ethnicity (non-Hispanic White, African-American, Hispanic-American and Asian-American), education (high school or less, some college, college graduate and more than college), current BMI and simultaneously for all the other variables shown.

^bAge 50 BMI and age 60 BMI were adjusted for in separate models replacing current BMI in the model.