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Loss of Stat5a alleles in combination with deregulated ERα led to a delayed terminal end bud differentiation. Graphs representing the number of TEBs in WT, CERM, CERM/Stat5a+/−, CERM/Stat5a−/−, Stat5a+/− and Stat5a−/− mice at 2 (A), 4 (B) and 12 months of age (C). Horizontal lines between genotypes demonstrating statistically significant differences in TEB number (*P < 0.05); mean ± SEM indicated.
