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. Author manuscript; available in PMC: 2010 May 28.
Published in final edited form as: Braz J Med Biol Res. 2009 Jan;42(1):94–104. doi: 10.1590/s0100-879x2009000100014

Figure 6.

Figure 6

Calculated radial decay of steady-state Ca2+ around the channel pore under the influence of the three Ca2+ buffers used: 0.05 mM BAPTA, 0.2 and 5 mM EGTA. The decay was calculated as described in Ref. 2 using a single exponential decay function with a space constant (λ) calculated using the formula: λ = (DCaτ)1/2, where DCa is the diffusion coefficient of Ca2+ and τ is a time constant calculated using the formula: τ = 1/(konB), where kon is the buffer association constant and B is the buffer concentration. Values used were: DCa = 5·10−6·cm−1; konBAPTA = 4·108 M−1·s−1; konEGTA = 2.5·106 M−1·s−1.