Table 2.
Neuropsychological Test Comparisons by Treatment Group Using Repeated Measure ANCOVAs with Gender, Age and Years of Education as Covariates.
| Modafinil Group N = 59 |
Placebo Group N = 44 |
|||||
|---|---|---|---|---|---|---|
| TEST | Baseline | Week 4 | Baseline | Week 4 | Interaction Term: Time by Group F |
p |
| WHO AVLT: Trial 1–5 Total | 47 (10) | 53 (10) | 47 (10) | 51 (11) | 1.383 | .243 |
| Delay 1 | 9.6 (2.8) | 11.2 (2.7) |
9.4 (2.5) | 10.3 (2.8) | 1.211 | .274 |
| Delay 2 | 9.7 (2.9) | 11.5 (2.6) |
9.5 (2.8) | 10.7 (2.9) | 1.920 | .169 |
| Recognition | 13.5 (1.8) | 14.2 (1.3) |
13.5 (1.8) | 13.9 (1.2) | .748 | .389 |
| WAIS: Digit Symbol | 66 (14.6) | 74 (16.6) | 69 (14.4) | 72 (15.4) | 8.583 | .004 * |
| Digit Span | 16 (4.5) | 17 (4.3) | 16 (3.9) | 17 (3.8) | .007 | .933 |
| Symbol Search | 31 (9) | 32 (9) | 29 (7) | 31 (9) | .489 | .486 |
| Letter-Number Sequence | 9.6 (2.5) | 10.0 (2.8) |
9.3 (2.6) | 9.5 (3.0) | .658 | .419 |
| Stroop: Words | 95 (18) | 99 (18) | 98 (14) | 99 (13) | 1.531 | .219 |
| Colors | 68 (13) | 71 (14) | 67 (13) | 67(12) | 3.384 | .069 |
| C-W | 40 (9) | 43 (9) | 38 (8) | 40 (8) | 2.081 | .152 |
| Interference | 0.57 (7.03) |
2.46 (6.56) |
−1.91 (6.15) |
−0.02 (6.79) |
.001 | .972 |
| Color Trails: 1 | 41 (17) | 35 (15) | 47 (21) | 42 (21) | .053 | .819 |
| 2 | 90 (39) | 83 (33) | 95 (35) | 88 (29) | .001 | .976 |
| Grooved Peg: Dominant Hand | 71 (14) | 67 (12) | 72 (17) | 70 (14) | .834 | .363 |
| Non-Dominant | 79 (19) | 73 (15) | 79 (19) | 78 (20) | 3.963 | .049 * |
| Verbal Fluency: FAS Letters | ||||||
| Total | 36 (12) | 40 (11) | 41 (13) | 44 (14) | 1.866 | .175 |