Table 1.

Clinical, laboratory, renal biopsy and follow-up data

	Case 1	Case 2	Case 3	Case 4
Age	62	52	7	36
Sex	Male	Male	Female	Male
Fever	+	+	+	+
Arthralgia	+	+	+	+
Hemoptysis	−	+	−	−
Neurological	Seizures	−	Seizures, Bell's palsy	−
Blood pressure	160/100	150/90	210/120	150/100
Chest X-ray	Transient infiltrates in mid lung zones.	Multiple cavities in both lung fields [Figure 1]	−	Normal
Urinalysis	Protein 3+, 10–12 RBC's/hpf	Protein 4+, 20–25 RBCs/hpf	Protein 3+, 10–12 RBCs/hpf	Protein 3+, 10–12 RBC's
Urine protein creatinine ratio	5.2:1.0	15.2: 1.0	7:1	5.5:1
ESR	120 mm/hr	80 mm/hr	110/hr	75 mm/hr
Serum C3,C4	Normal	Normal	Normal	N
Blood urea/creatinine mg%	145/7.6	167/5.4	128/3.8	184/10
BVAS score	23/63	31/63	24/63	15/63
Renal biopsy	LM:10 glomeruli, one obsolescent. Focal proliferative lesions in four. Two showed cellular crescents. Interstitial fibrosis 21 IF: Negative	LM:8 glomeruli with mesangial proliferation. Four showed cellular crescents. Interstitial fibrosis 1+ IF: Negative	LM:7 glomeruli. Two obsolescent. Focal necrosis with crescents in two glomerulus. Interstitial fibrosis-3+ IF: Negative [Figure 2]	LM:29 glomeruli 26 showed crescents (89%) focal fibrinoid necrosis. Normal interstitium
Follow-up	36 months. current S. Cr. − 1.3 mg.	4 weeks. Died due to pulmonary hemorrhage	16 months. Current S. Cr. − 1.8 mg.	8 weeks. Current S.Cr. −2.4 mg%

LM: Light microscopy; S. Cr.: Serum creatinine; BUAS: Birmingham vasculitis assessment score