Table 1.

Summary of known receptors for P. falciparum adhesion

^aOwing to different clinical and epidemiological features of severe malaria in regions of varying malaria transmission, studies have been separated into ‘Africa’ and ‘Papua New Guinea’ indicating stable, moderate-high transmission areas where severe malaria affects young children and substantial immunity develops in the population, or ‘Asia’ indicating unstable or low transmission areas where severe malaria affects nonimmune individuals of all age groups.

^bND, not done.

^cSubphenotypes of rosetting and clumping involving individual receptors have not been examined for their relationship with disease severity.