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Hyperosmolar solutions reduced intracellular accumulation of GABARs during bursting. A, B, Color-merged images of antibody-tagged surface (green) and internalized (red) receptors for neurons incubated in either 0 [Mg]o (A, Bursting) or 0 [Mg]o supplemented with 350 mm sucrose (B, Bursting + Sucrose) at 37°C for 30 min after antibody tagging of the GABARs. Compared with bursting neurons, the addition of sucrose resulted in a reduction of the intracellular accumulation.
