FIGURE 6.

Comparison of α₁α₆β₃δ GABA_A receptors with α₁β₃δ and α₆β₃δ receptors. The table compares currents elicited by 1 mm GABA in the absence and presence of 1 μm THDOC and the EC₅₀ for GABA for all investigated variants of α₁β₃δ, α₆β₃δ, and α₁α₆β₃δ GABA_A receptors. Footnote a, the concentration-response curve was fitted with two components. The low affinity phase is mentioned in parentheses. Footnote b, the experiments were carried out in the presence of 1 μm THDOC. Footnote c, this receptor may not be formed for reasons discussed in Ref. 29. Footnote d, the corresponding pentameric construct did not result in expression.