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. 2010 Apr 12;285(23):17425–17431. doi: 10.1074/jbc.M109.091561

FIGURE 6.

FIGURE 6.

Extracellular Cl− modulates H+-gated currents in hippocampal neurons. A, superimposed pH 6-evoked currents recorded from a rat hippocampal neuron in either Cl− or SCN− solutions. B, mean time constants of desensitization of currents evoked by the indicated pH in either Cl− or SCN− solutions (n ≥ 9; *, p < 0.01 versus Cl−). C, mean current density of pH 5-evoked currents in either Cl− or SCN− solutions (n ≥ 9; *, p < 0.05 versus Cl−). D, pH dose-response curves for activation in either Cl− or SCN solutions normalized to the peak currents evoked by pH 5 (n ≥ 8). E, tachyphylaxis of successive pH 5-evoked current amplitudes normalized to the first pH 5 current amplitude recorded in either Cl− or SCN− solutions (n = 6).