. 2010 Mar 30;285(23):18051–18059. doi: 10.1074/jbc.M110.110833

TABLE 3.

Best fit folding parameters

Parameters and fitting errors for an off-pathway scheme at 25 °C and a triangular scheme at 37 °C, from simultaneous fits of the fast and slow phases to Equations 2 and 3, respectively (Fig. 3). The large errors in the fitting result from the large number of parameters and a limited data set. The double jump experiment (Fig. 4) was used to verify the kinetic schemes.

	k_DI	k_ID	k_DN	k_ND	k_IN	k_NI	m_DI	m_ID	m_DN	m_ND	m_IN	m_NI
	s⁻¹	s⁻¹	s⁻¹	s⁻¹	s⁻¹	s⁻¹	kcal mol⁻¹m⁻¹	kcal mol⁻¹m⁻¹	kcal mol⁻¹m⁻¹	kcal mol⁻¹m⁻¹	kcal mol⁻¹m⁻¹	kcal mol⁻¹m⁻¹
Off-pathway 25 °C	0.07 ± 1.6	0.026 ± 0.028	2.1 ± 2.2	0.002 ± 0.001			0.5 ± 5	0.22 ± 0.09	1.0 ± 0.13	0.31 ± 0.05
Triangular 37 °C	2.5 ± 4.1	0.020^a	0.9 ± 6.5	0.0009 ± 0.007	0.11 ± 0.06	0.014 ± 0.013	0.72 ± 0.49	0.44^b	1.4 ± 2.5	0.39 ± 2.5	0.30 ± 0.33	0.37 ± 0.21

^a Calculated from the five fitted rate constants.

^b Calculated from the five fitted m values.