TABLE 4.

Best fit parameters from interrupted refolding experiments (Fig. 4)

Also shown is a comparison with observed rate constants from the single jump experiments in Fig. 3.

Experiment/phase	Double jump experiment				Single jump at 1 m urea
	kobs1	Amplitude 1	kobs2	Amplitude 2	kobs1	kobs2
	s−1		s−1		s−1	s−1
37 °C slow phase	0.77 ± 0.16	0.84 ± 0.12	0.090 ± 0.013	1.14 ± 0.12	0.91	0.095
37 °C fast phase	0.77a	1.26 ± 0.19	0.090a	0.77 ± 0.21
25 °C slow phase	0.60 ± 0.30	1.1 ± 0.3	0.045 ± 0.013	1.9 ± 0.3	0.43	0.049
25 °C fast phase	0.60a	0.61 ± 0.15	0.045a	0.03 ± 0.17

^a The amplitude of the fast phase from the double jump experiment yields large fitting errors upon free fitting. Therefore the rate constants obtained from free fitting of the slow phases were used to constrain the fitting of the amplitudes from the fast phase.