Table 3.
PPH (≥500 ml) and severe PPH (≥1000 ml) by third-stage prophylactic regimen
| Prophylactic regimen | Study | % PPH | % Severe PPH | Ratio % Severe PPH to PPH |
|---|---|---|---|---|
| No uterotonic | Angola: Strand, 200526 | 40.41 | 7.42 | 18.36 |
| France: Benchimol, 200147 | 27.27 | 5.91 | 21.67 | |
| Guinea Bissau, rural: Høj, 200542 | 51.36 | 16.92 | 32.94 | |
| India, rural: Derman, 200624 | 12 | 1.24 | 10.33 | |
| Ireland: Begley, 199049 | 8.29 | 1.52 | 18.34 | |
| The Netherlands, multicenter: de Groot, 199650 | 38.46 | 11.19 | 29.10 | |
| The Netherlands: Poeschmann, 199135 | 41.67 | 12.5 | 30.00 | |
| South Africa: Bamigboye, 199828 | NR | 6.99 | ||
| South Africa: Hofmeyr, 199823 | NR | 9.2 | ||
| South Africa: Hofmeyr, 200143 | NR | 9.7 | ||
| Sweden: Nordstrom, 199725 | 35.93 | 8.83 | 24.58 | |
| Vietnam: Tsu, 200632 | 3.84 | 0.51 | 13.28 | |
| Oxytocin | Angola: Strand, 200526 | 8.23 | 0.98 | 11.91 |
| Egypt: Abdel-Aleem, 200648 | 4.08 | NR | ||
| Egypt: Abdel-Aleem, 200648 | 7.84 | NR | 41.38 | |
| France: Benchimol, 200147 | 14.79 | 6.12 | 41.38 | |
| Hong Kong: Yuen, 199530 | 12.12 | 2.02 | 16.67 | |
| India: Gupta, 200644 | 0 | NR | ||
| India: Zachariah, 200629 | 2.11 | 0.65 | 30.81 | |
| Israel: Soriano, 199633 | 9.73 | NR | ||
| Japan: Fujimoto, 200651 | 11.58 | NR | ||
| Japan: Fujimoto, 200651 | 7.32 | NR | ||
| Multicentre Gulmezoglu, 200140 | 13.53 | 2.85 | 21.06 | |
| The Netherlands, multicentre: de Groot, 199650 | 32.05 | 8.97 | 27.99 | |
| The Netherlands: Poeschmann, 199135 | 25.0 | 7.14 | 28.56 | |
| Sweden: Nordstrom, 199725 | 20.27 | 6.24 | 30.78 | |
| UAE: Khan, 199741 | 10.96 | 3.17 | 28.92 | |
| UAE: Khan, 199741 | 5.8 | 0.73 | 12.59 | |
| UK: Mitchell, 199341 | 7.39 | 0.43 | 5.82 | |
| Vietnam: Tsu, 200632 | 2.67 | 0.73 | 27.34 | |
| Zimbabwe: Kundodyiwa, 200140 | 13.28 | 1.95 | 14.68 | |
| Misoprostol | Egypt: Prata, 200634 | 1.61 | 0.08 | 4.97 |
| France: Benchimol, 200147 | 27.95 | 8.6 | 30.77 | |
| Gambia, rural: Walraven, 200553 | 10.97 | 0.32 | 2.92 | |
| Guinea Bissau, rural: Høj, 200542 | 45.45 | 11.21 | 24.66 | |
| Hong Kong: Lam, 200439 | 13.33 | NR | ||
| India, rural: Derman, 200624 | 6.4 | 0.25 | 3.91 | |
| India: Gupta, 200644 | 1 | |||
| India: Verma, 200631 | 1 | NR | ||
| India, rural: Vimala, 200452 | 3.33 | 0 | 0 | |
| India: Zachariah, 200629 | 2.6 | 0.14 | 5.38 | |
| South Africa: Bamigboye, 199828 | 4.81 | |||
| South Africa: Hofmeyr, 199823 | NR | 6.0 | ||
| South Africa: Hofmeyr, 200143 | NR | 9.0 | ||
| Zimbabwe: Kundodyiwa, 200140 | 15.23 | 3.7 | 24.29 | |
| Multicentre Gulmezoglu, 200140 | 19.46 | 3.97 | 20.40 | |
| Ergometrine | Gambia, rural: Walraven, 200553 | 12.02 | 0.67 | 5.57 |
| India: Verma, 200631 | 0 | NR | ||
| India, rural: Vimala, 200452 | 0 | 0 | 0 | |
| India: Zachariah, 200629 | 2.96 | 0.89 | 30.07 | |
| Ireland: Begley, 199049 | 1.99 | 0.14 | 7.04 | |
| Japan: Fujimoto, 200651 | 7.59 | NR | ||
| Japan: Fujimoto, 200651 | 18.57 | NR | ||
| The Netherlands, multicentre: de Groot, 199650 | 36.99 | 8.22 | 22.22 |
NR, not reported.