Table 1.
Baseline characteristics of the study participants.
| CHOL (mg/dl) |
TG (mg/dl) |
HDL (mg/dl) |
LDL (mg/dl) |
APOA1 (mg/dl) |
APOB (mg/dl) |
||
|---|---|---|---|---|---|---|---|
| GG n=50 | 153.61 ± 3.39 | 86.7 ± 4.6 | 45.64 ± 1.38 | 90.68 ± 3.1 | 103.64 ± 2.55 | 67.88 ± 2.48 | |
|
ABCA1 R219K |
GA/AA n=34/4 | 150.48 ± 3.61 | 72.90 ± 5.5 | 47.01 ± 1.83 | 88.84 ± 3.46 | 109.36 ± 3.58 | 67.72 ± 2.53 |
| (rs2230806) | p | 0.537 | 0.056 | 0.545 | 0.695 | 0.184 | 0.965 |
| CC n=23 | 152.54 ± 4.78 | 73.64 ± 7.29 | 50.061 ± 2.07* | 88.05 ± 4.07 | 116.43 ± 4.04* | 63.50 ± 3.13 | |
|
ABCA1 i48168 |
CT n=51 | 152.82 ± 3.06 | 80.76 ± 4.67 | 45.36 ± 1.32 | 90.72 ± 3.2 | 103.59 ± 2.59 | 69.16 ± 2.00 |
| (rs4149272) | TT n=14 | 149.33 ± 5.85 | 81.56 ± 8.93 | 45.389 ± 2.53 | 87.4 ± 5.38 | 106.75 ± 4.95 | 67.30 ± 3.83 |
| p | 0.867 | 0.685 | 0.041 | 0.820 | 0.033 | 0.310 | |
| GG n=21 | 152.12 ± 5.00 | 75.63 ± 7.67 | 49.36 ± 2.21 | 85.36 ± 5.74 | 115.78 ± 4.28† | 63.88 ± 3.29 | |
|
ABCA1 i27943 |
GA n=52 | 153.347 ± 2.99 | 79.88 ± 4.59 | 45.89 ± 1.32 | 91.39 ± 3.02 | 104.00 ± 2.56 | 69.06 ± 1.97 |
| (rs2575875) | AA n=15 | 147.86 ± 5.83 | 81.17 ± 8.93 | 46.12 ± 2.57 | 87.46 ± 4.44 | 107.89 ± 4.98 | 66.38 ± 3.82 |
| p | 0.707 | 0.867 | 0.395 | 0.574 | 0.039 | 0.385 | |
The p-value in each cell corresponds to univariate ANOVA, with each genotype as independent factor and each phenotype variable as dependent factor (with age and BMI as covariates). Within each cell, the upper genotype corresponds to homozygotes for the major allele, the intermediate to heterozygotes, and the lower to homozygotes for the minor allele. All values are mean ±SE. Superscripts in cells are as follows:
=p<0.05 ABCA1 i48168 CC vs CT.
=p<0.05 ABCA1 i27943 GG vs GA