Figure 2.
Final drug payload as a function of loading method and initial concentration (a), and corresponding encapsulation efficiency (b). H-Dox-UCA = , I-Dox-UCA =
, S-Dox-UCA =
. H-Dox-UCA approached a maximal drug load of 24.1 mg Dox/g PLA (encapsulation efficiency of 60.2%) at an initial loading concentration of 40.0 mg Dox/g PLA. Both the I-Dox-UCA and S-Dox-UCA samples reached peak drug payloads of 6.2 and 6.5 mg Dox/g PLA (encapsulation efficiencies of 20.5 and 21.9%) respectively at an initial loading concentration of 30.0 mg Dox/g PLA.