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Mutation spectrum of AID hybrids in rpoB gene.
Frequency of mutations at six positions in the rpoB gene is shown. The position of the target cytosine within the gene and the sequence context of this cytosine are indicated. At positions 1546 and 1586 the deaminated cytosine is in the template strand. The sequence shown is in the non-template strand.
A. AID with regions from A3G.
B. Ratio of the frequency of mutations at position 1691 to that at position 1586.
