Table 4.
Behavioral, subjective, and motor results (means [±SD])
| Outcome | Placebo haloperidol |
Active haloperidol |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| −90 | −30 | 15 | 65 | 140 | 190 | −90 | −30 | 15 | 65 | 140 | 190 | ||
| Pre THC | Placebo THC | Active THC | Pre THC | Placebo THC | Active THC | ||||||||
| PANSS | Positive | 7.7 (0.76) | 7.78 (0.8) | 7.78 (0.8) | 7.87 (0.81) | 9.13 (1.39) | 8.26 (1.14) | 7.76 (0.93) | 7.88 (1.05) | 7.92 (1.08) | 8.04 (1.17) | 8.64 (1.29) | 8.25 (1.54) |
| Total | 30.7 (3.53) | 30.83 (2.72) | 31.04 (3.08) | 30.83 (2.44) | 35.5 (3.6) | 31.39 (2.25) | 30.44 (2.65) | 30.6 (2.6) | 30.96 (2.79) | 31.36 (3.05) | 34.58 (2.89) | 32.21 (3.27) | |
| CADSS | Subject rated | 0.22 (0.6) | 0.26 (0.69) | 0.13 (0.46) | 0.22 (0.6) | 3.96 (4.64) | 1.17 (2.12) | 0.28 (0.68) | 0.32 (1.07) | 0.38 (0.77) | 0.2 (0.58) | 2.24 (2.68) | 0.84 (1.57) |
| Clinician rated | 0.09 (0.29) | 0.14 (0.35) | 0.17 (0.65) | 0.17 (0.65) | 2.43 (2.74) | 0.52 (1.08) | 0.04 (0.2) | 0 (0) | 0.24 (0.6) | 0.28 (0.89) | 1.96 (2.07) | 0.92 (1.41) | |
| VAS | Anxious | 5.52 (13.5) | 3.65 (10.45) | 1.7 (4.19) | 2.65 (6.11) | 4.13 (8.15) | 1.91 (5.2) | 8.8 (13.3) | 4.48 (9.24) | 2.92 (5.28) | 1.4 (2.74) | 4.28 (10.44) | 6.96 (19.77) |
| Calm | 76.91 (21.9) | 78.96 (20.5) | 76.74 (25.65) | 76.74 (23.86) | 80.13 (25) | 80.43 (19.82) | 69.76 (27.16) | 74.2 (25.31) | 77.76 (18.82) | 72.96 (23.36) | 73.6 (30.7) | 70.67 (25.65) | |
| High | 0.48 (0.99) | 0.7 (1.11) | 2.52 (5.23) | 2.04 (4.57) | 39.32 (31.15) | 18.13 (20.9) | 0.12 (0.33) | 2.72 (10.06) | 2.4 (5.63) | 1.13 (4.08) | 34.96 (30.71) | 18.88 (21.88) | |
| Panic | 0.65 (1.23) | 0.65 (1.19) | 0.57 (0.95) | 0.61 (1.12) | 0.74 (1.18) | 0.91 (1.44) | 0.28 (0.61) | 0.32 (0.69) | 0.48 (1.05) | 0.4 (0.87) | 1.4 (3.11) | 1.29 (2.58) | |
| Tired | 24.26 (25.5) | 28.13 (28.88) | 29.52 (24.26) | 24 (25.39) | 34.09 (25.91) | 22.3 (27.26) | 13.4 (18.31) | 19.28 (22.47) | 24.4 (25.7) | 27.12 (27.22) | 36.56 (26.42) | 26 (26.36) | |
| Similarity to cannabis | 4.13 (10.99) | 59.17 (30.64) | 5.52 (15.58) | 55.24 (29.65) | |||||||||
| Enjoyment of experience | 31.43 (25.97) | 61.04 (26.64) | 19.88 (22.98) | 47 (26.24) | |||||||||
PANSS Positive and Negative Syndrome Scale, CADSS Clinician Administered Dissociative Symptoms Scale, VAS visual analog scale