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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: J Autoimmun. 2010 Jan 12;35(1):1–9. doi: 10.1016/j.jaut.2009.12.007

Figure 6.

Figure 6

Cytokines produced (pg/ml) in response to CII-derived peptides by B cells and DCs show a different profile in male and female transgenic mice. Cytokine produced in response to DR4-restricted CII-derived peptide 254-273 in vitro by A) B cells and B) DCs in *0401 mice. Both sexes produced IFNγ above detection limits when presented by B cells and DCs (not shown). Cytokines produced in *0401/DQ8 mice in response to presentation of C) DR4-restricted CII peptide 254-273 and D) DQ8-restricted CII peptide 284-303 by B cells and DCs.