Table1.
Collagen-induced arthritis in male and female transgenic mice.
| Mice | Incidence (%) |
Onset | Severity |
|---|---|---|---|
| 0401/DQ8 | |||
| M | 5/12 (41) | 7±1 | 6.3±1.5 |
| F | 10/12 (83) | 5.2±1.5 | 6.4±1.3 |
| Total | 15/24(63) | 5.5±1.6 | 6.4±1.2 |
| 0402/DQ8 | |||
| M | 2/14 (14) | 5±0 | 7±1.4 |
| F | 5/11(45) | 5±0.7 | 6.8±1.8 |
| Total | 7/25 (28) | 5±0.5 | 6.8±1.6 |
| 0402 | |||
| M | 2/17 (12) | 8±4.2 | 3.5±3.5 |
| F | 6/26 (23) | 6.3±2.1 | 4.8±2.9 |
| Total | 8/43 (19) | 6.7±2.5 | 4.5±2.9 |
| DQ8 | |||
| M | 6/9(67) | 6.2±2.1 | 6.2±3.5 |
| F | 8/11 (73), | 5.6±2.6 | 7.2±1.8 |
| Total | 14/20 (70) | 5.8±2.3 | 6.7±2.5 |
*0401/DQ8 Female vs Male, p=0.04
*0402.DQ8 vs DQ8, Male, p=.02
*0401/DQ8 vs *0402/DQ8, p=0.02
*0402/DQ8 vs DQ8, p=0.005