. Author manuscript; available in PMC: 2011 Jul 1.

Published in final edited form as: Ageing Res Rev. 2009 Nov 10;9(3):315–323. doi: 10.1016/j.arr.2009.10.006

Table 1.

Comparison between the most common NGS platforms

Platform	454	Illumina/Solexa	SOLiD
Sequence data per run	400–600 Mb	>25,000 Mb	>20,000 Mb
Read length (bases)	400–500	35–75	50
Cost per MB	~$60	~$2	~$2

Notes: Platform specifications for 454 (http://www.454.com), Illumina/Solexa (http://www.illumina.com) and SOLiD (http://solid.appliedbiosystems.com). Costs are estimates taken from Shendure and Ji (2008). Given the dynamic nature of the NGS field, the above values are meant as a snapshot of current NGS platforms and are likely to be outdated soon.