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Comparison of prevalence of autoimmune diseases in SSc and control families after adjustment for sibship size and proband’s age
| Lifetime FDR prevalence (n = 4612)* |
Lifetime control prevalence (n = 1315) |
Odd ratio |
95% CI | p-value | |
|---|---|---|---|---|---|
| Hypothyroidism | 10% | 4.3% | 2.51 | 1.46–4.62 | >0.001 |
| Hyperthyroidism | 4.3% | 1.6% | 2.76 | 1.16–7.97 | 0.016 |
| RA | 7% | 7.2% | 0.97 | 0.61–1.59 | 0.9 |
| SLE | 2.2% | 0% | 16.98 | 1.02–227.8 | 0.004 |
Familial prevalence in the FDRs of patients with SSc.
