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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: J Autoimmun. 2010 Mar 11;35(1):52–57. doi: 10.1016/j.jaut.2010.02.001

Table 5.

Results of autoantibodies in SSc patients, their FDRs and controls

Cases
(n = 1058) (%)		 FDRs
(n = 1005)″		 Controls*
(n = 644)″		 Spouses
(n = 186)″
ANA (%) 967 (91.4) 143 (14.2) 68 (10.6) 16 (8.6)
Diffuse speckled (%) 522 (49.3) 122 (12.1) 54 (8.3) 12 (6.4)
Nucleolar (%) 291 (27.5) 20 (1.9) 9 (1.4) 3 (1.6)
Centromere (%) 286 (27.0) 2 (0.2) 0 (0) 0 (0)
Cytoplasmic (%) 117 (11.0) 30 (2.9) 5 (0.7) 2 (1.1)
Anti-mitochondrial (%) 29 (2.7) 14 (1.4) 1 (0.1) 0 (0)
Anti-Ro (%) 46 (4.3) 4 (0.4) 2 (0.3) 0 (0)
Anti-La (%) 11 (1.0) 0 (0) 0 (0) 0 (0)
Anti-RNP (%) 193 (18.2) 4 (0.4) 0 (0) 0 (0)
Anti-Topo-1 (%) 216 (20.4) 0 (0) 0 (0) 0 (0)
*

Controls include both spousal and non-spousal controls.