Table 1.
Young | Aging | |||||
---|---|---|---|---|---|---|
Control | Phd2 CKO | p valueb | Control | Phd2 CKO | p valueb | |
Neutrophils | 2.7 ± 1.7 | 13.1 ± 10 | < 0.05 | 3.9 ± 1.8 | 8.5 ± 3.3 | < 0.01 |
Monocytes | 0.96 ± 0.33 | 4.3 ± 4.8 | 1.5 ± 0.26 | 2.1 ± 0.33 | < 0.01 | |
Eosinophils | 0.54 ± 0.4 | 2 ± 1.5 | < 0.05 | 0.78 ± 0.52 | 1.7 ± 0.45 | < 0.01 |
Basophils | 0.17 ± 0.12 | 0.49 ± 0.3 | < 0.05 | 0.21 ± 0.19 | 0.5 ± 0.2 | < 0.01 |
Lymphocytes | 8.1 ± 2.8 | 10.9 ± 2.5 | 8.9 ± 3.3 | 12.3 ± 2.3 | < 0.05 |
Values for all cell types are in 106/µL. Measurements were made four weeks after the initial tamoxifen dose. For each group, n = 6–8. Young = 6 to 8 months, aging = 16 to 20 months.
p values are for the comparison between Controls and Phd2 CKO mice in a given age group