Table 2.
Joint Modeling of MMSE Score and Survival Time
| Covariate | Estimate | Standard Error | p-value | |
|---|---|---|---|---|
| MMSE Score | ||||
| Assessment time (Time) | −0.0132 | 0.0064 | 0.0413 | |
| Treatment arms (RX) (PCV+RT) | 0.2398 | 0.3354 | 0.4752 | |
| Interaction between treatment and time | 0.0120 | 0.0090 | 0.1832 | |
| KPS (80–100) | 2.7240 | 0.5412 | <.0001 | |
| Age (<50) | 1.4106 | 0.3479 | <.0001 | |
| Anaplastic features (2–3) | 0.2981 | 0.3146 | 0.3441 | |
| Surgery (Resection) | 0.5322 | 0.4999 | 0.2879 | |
| Multifocal (No) | 0.2094 | 0.5909 | 0.7233 | |
| 1p/19q deletion (Both deleted) | 0.1785 | 0.3209 | 0.5786 | |
| Hazard Ratio (95% CI) | ||||
| Survival Time | ||||
| Treatment arm (PCV+RT) | 0.3556 | 0.1339 | 0.0084 | 0.66 (0.49,0.90) |
| KPS (80–100) | 0.5613 | 0.1990 | 0.0051 | 0.52 (0.33,0.82) |
| Age (<50) | 0.4642 | 0.1498 | 0.0021 | 0.58 (0.41,0.82) |
| Anaplastic features (2–3) | 0.4825 | 0.1369 | 0.0005 | 0.57 (0.42,0.78) |
| Surgery (Resection) | 0.4572 | 0.2010 | 0.0237 | 0.59 (0.37,0.93) |
| Multifocal (No) | 1.0238 | 0.2167 | <.0001 | 0.30 (0.18,0.50) |
| 1p/19q deletion (Both deleted) | 0.7370 | 0.1358 | <.0001 | 0.42 (0.31,0.58) |