. Author manuscript; available in PMC: 2011 Jul 1.

Published in final edited form as: Neurobiol Dis. 2010 Mar 20;39(1):105–115. doi: 10.1016/j.nbd.2010.03.009

Table 1. Levels of DA, DOPAC and HVA in the Striatum and Frontal Cortex.

	Hemisphere	Stimulation	DA	HVA	DOPAC
Striatum	Contra	Inactive Stim	179.6 ± 42.2	14.4 ± 3.3	16.6 ± 4.2
	Contra	Active Stim	223.7 ± 17.4	14.7 ± 1.2	19.6 ± 2
	Ipsi	Inactive Stim	3.9 ± 2.1*	4.0 ± 2.3*	2.5 ± 1.5*
	Ipsi	Active Stim	2.4 ± 1.1*	0.8 ± 0.8*	1.7 ± 0.6*
Cortex	Contra	Inactive Stim	3.1 ± 0.3	3.6 ± 2.0	2.2 ± 1.2
	Contra	Active Stim	3.6 ± 3.4	4.8 ± 0.7	3.0 ± 0.6
	Ipsi	Inactive Stim	2.4 ± 0.5*	b.d.l.*	1.6 ± 0.7
	Ipsi	Active Stim	2.6 ± 0.3*	b.d.l.*	0.7 ± 0.7

Rats in both the ACTIVE stimulation group and the INACTIVE control group exhibited a significant loss of DA, DOPAC and HVA within the ipsilateral striatum and a significant loss of DA and HVA in the frontal cortex as a result of intrastriatal 6-OHDA (*, p<0.001). No significant differences were observed in the levels of any of the catecholamines examined in either structure as a result of ACTIVE stimulation of the STN (p>0.05). Values are expressed in units of ng/mg protein ± S.E.M. Below detectable limits = b.d.l.