(A) Systolic blood pressure was measured in SR and SS rats at baseline and at weekly intervals during administration of high-salt diet alone (HSD, 8% NaCl; SR+HSD and SS+HSD) or supplemented with fish oil (FO, 25%; SS+HSD+FO). Values are mean ± SEM (n=10). #P<0.05 vs. SR+HSD, *P<0.05 vs. SS+HSD. (B) Rats were treated with normal-salt diet (NSD, 0.45% NaCl; SS+NSD, n=3), high-salt diet alone (SR+HSD and SS+HSD, n=10), or high-salt diet supplemented with hydralazine (HYD, 5 mg/kg/d; SS+HSD+HYD, n=6) or fish oil (SS+HSD+FO, n=10). Blood pressure was measured at baseline and after 4 weeks on diet. Values are mean ± SEM. #P<0.05 vs. SS+NSD, *P<0.05 vs. SS+HSD, +P<0.05 vs. SS+HSD+HYD.