(A) 24 hour urine protein excretion was assessed at baseline and at weekly intervals in SS rats fed diets containing normal salt (NSD, 0.45% NaCl; SS+NSD, n=3), high salt (HSD, 8% NaCl; SS+HSD, n=10), or high salt with hydralazine (HYD, 5 mg/kg/d; SS+HSD+HYD, n=6). Values are mean ± SEM. #P<0.05 vs. SS+HSD. (B) 24 hour urine protein was measured at baseline and after 4 weeks in rats on normal-salt diet (SS+NSD, n=3), high-salt diet alone (SR+HSD and SS+HSD, n=10), or high-salt diet supplemented with hydralazine (SS+HSD+HYD, n=6) or fish oil (SS+HSD+FO, n=10). Values are mean ± SEM. #P<0.05 vs. SS+NSD, *P<0.05 vs. SS+HSD, +P<0.05 vs. SS+HSD+HYD.