SR and SS rats were maintained for 4 weeks on high-salt diet alone (SR+HSD and SS+HSD), or supplemented with corn oil (SS+HSD+CO), hydralazine (SS+HSD+HYD), or fish oil (SS+HSD+FO) as indicated. Histologic sections of renal tissue were stained with Sirius red or Masson's trichrome; staining was quantitated, relative to cortical surface area, with the MetaVue Image Analysis System. Values are mean ± SEM (n=10). #P<0.05 vs. SR+HSD, *P<0.05 vs. SS+HSD, +P<0.05 vs. SS+HSD+CO, §P<0.05 vs. SS+HSD+HYD. Images = representative trichrome stains.