. Author manuscript; available in PMC: 2010 Jun 1.

Published in final edited form as: J Neurooncol. 2008 Sep 1;91(1):19–26. doi: 10.1007/s11060-008-9683-5

Table 1.

Correlations between signaling molecules and glioma grade

Groups	Normal vs. tumor P-value	Spearman’s Correlation Coefficient		P values for pairwise comparisons
Groups	Normal vs. tumor P-value	SCC	P-value	Normal vs Gr. 2	Normal vs Gr. 3	Normal vs Gr. 4	Gr. 2 vs Gr. 3	Gr. 3 vs Gr. 4	Gr. 2 vs Gr. 4
pS6	0.433	0.049	0.687	0.230	0.182	0.478	0.212	0.028	0.121
p4E-BP1	0.000	0.334	0.004	0.000	0.000	0.020	0.155	0.221	0.908
pPKB	0.005	0.396	0.000	0.123	0.006	0.002	0.011	0.502	0.014
PTEN	0.093	−0.517	0.000	0.845	0.451	0.000	0.233	0.005	0.000
TSC1 mRNA	0.000	−0.736	0.000	0.483	N/A^*	0.000	N/A^*	N/A^*	0.001
TSC1 protein	0.000	−0.694	0.000	0.224	N/A^*	0.000	N/A^*	N/A^*	0.000
TSC2 mRNA	0.002	−0.578	0.000	0.586	N/A^*	0.000	N/A^*	N/A^*	0.008
TSC2 protein	0.001	−0.798	0.000	0.870	N/A^*	0.000	N/A^*	N/A^*	0.000

No Grade 3 in TSC1 and TSC2 analyses