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Renal AngII content (a) and mRNA level of AGT (b) and renin (c) in renal cortical tissues. SHR/ND had higher renal AngII levels and mRNA levels of AGT and renin compared with WKY. Cilnidipine treatment decreased renal AngII and AGT levels, but amlodipine had no effect. *P < 0.05, **P < 0.01 vs. WKY, #P < 0.05 vs. SHR/ND, †P < 0.05 vs. SHR/ND + amlodipine (n = 11–12). SHR, spontaneously hypertensive rat; WKY, Wistar-Kyoto rats.
