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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: J Mol Cell Cardiol. 2009 Jul 15;48(1):211–219. doi: 10.1016/j.yjmcc.2009.07.003

Figure 6.

Figure 6

Representative current traces in isotonic condition and under hypotonic challenge in the freshly isolated atrial myocytes from age-matched cardiac-specific ClC-3 inducible knock-out mice. (A) Mice maintained on doxycycline, and (B) mice after 3 weeks off doxycycline. (C) is a summary of current densities under isotonic and hypotonic solutions, recorded at +80 mV and −80 mV, in freshly isolated atrial myocytes from age-matched cardiac-specific ClC-3 inducible knock-out mice, either maintained on doxycycline (n=14, 5 mice), or off doxycycline for 1.5 weeks (n=11, 3 mice) or 3 weeks (n=17, 4 mice). Open boxes, under isotonic conditions, filled boxes under hypotonic conditions. Grey boxes on doxycycline, black boxes off doxycycline 1.5 weeks and pale grey boxes off doxycycline for 3 weeks. ** p<0.01, hypotonic-induced VSOAC current densities compared to isotonic conditions. ## p<0.01, hypotonic-induced VSOAC current densities compared between on doxycycline and 1.5 weeks off doxycycline, and between 1.5 and 3 weeks off doxycycline using ANOVA.

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