Table 4.
Influence of GFR, age, body weight, BMI, and gender on the absolute bias
| Parameter | Cockcroft-Gault | MDRD | CKD-EPI |
|---|---|---|---|
| GFR (ml/min per 1.73 m2) | 0.030 (−0.030 to 0.090) | 0.150 (0.070 to 0.220) | 0.050 (0.004 to 0.100) |
| Age (years) | −0.26 (−0.38 to −0.14) | −0.27 (−0.43 to −0.11) | −0.17 (−0.27 to −0.07) |
| Body weight (kg) | 0.140 (0.040 to 0.25) | −0.130 (−0.270 to 0.004) | −0.090 (−0.170 to 0.003) |
| BMI (kg/m2) | 0.55 (0.23 to 0.88) | −0.14 (−0.57 to 0.29) | −0.21 (−0.47 to 0.05) |
| Female gender | 3.57 (−0.09 to 7.23) | 7.77 (3.06 to 12.47) | 2.19 (−0.72 to 5.10) |
The numbers represent the change of the absolute bias in ml/min per 1.73 m2 for an increase per unit of the given variables (β values) and their accompanying 95% CIs. One unit of GFR represents 1 ml/min per 1.73 m2; for age, one unit represents 1 year; for body weight, one unit represents 1 kg; for BMI, one unit represents 1 kg/m2; and for gender one unit represents being a woman compared with being a man.