Table 1.
Characteristics of ADPKD patients (n = 103) and of age- and gender-matched healthy controls (live kidney donors, n = 103)a
| Variable | ADPKD Patients | Healthy Controls | P |
|---|---|---|---|
| Age (years) | 40 ± 11 | 40 ± 10 | 0.92 |
| Male gender, n (%) | 60 (58) | 60 (58) | 1.00 |
| BMI (kg/m2) | 26.1 ± 4.6 | 25.6 ± 3.8 | 0.47 |
| MAP (mmHg) | 96 ± 9 | 92 ± 9 | <0.001 |
| Antihypertensive medication, n (%) | 80 (78) | 2 (2) | <0.001 |
| TRV (L) | 1.49 (0.95 to 2.19) | – | – |
| Hb (mmol/L) | 8.4 ± 0.8 | 8.9 ± 0.8 | <0.001 |
| Serum creatinine (μmol/L) | 111 ± 68 | 74 ± 11 | <0.001 |
| GFR (ml/min) | 92 ± 36 | 124 ± 20 | <0.001 |
| ERPF (ml/min) | 301 ± 125 | 475 ± 84 | <0.001 |
| FF | 30 ± 4 | 26 ± 3 | <0.001 |
| RVR (dynes/cm−2) | 16.1 (11.6 to 21.8) | 8.8 (7.9 to 1.0) | <0.001 |
a
Parametric variables are expressed as mean ± SD, whereas nonparametric variables are given as median (25th to 75th percentile).