Table 2.
Within Group Comparisons
| Region | Side | BA | Talairach Coords (x,y,z) | t-value | Region | Side | BA | Talairach Coords (x,y,z) | t-value | Region | Side | BA | Talairach Coords (x,y,z) | t-value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ASD Group | CA Group | MA Group | ||||||||||||
| Forward Speech > Rest | ||||||||||||||
| Temporal | Temporal | Frontal | ||||||||||||
| Superior Temporal Gyrus | L | 22 | (−54,−5,−2) | 4.61 | Superior Temporal Gyrus | L | 22 | (−63,−18,3) | 5.39 | Medial Frontal Cortex | L | 32 | (−10,46,6) | 4.19 |
| Superior Temporal Gyrus | R | 42/22 | (64,−21,7) | 5.72 | Superior Temporal Gyrus | L | 22 | (−46,−21,2) | 3.64 | Middle Frontal Gyrus | L | 10 | (−31,54,3) | 5.47 |
| Transverse Temporal Gyrus | R | 42 | (50,−6,6) | 5.79 | Middle Temporal Gyrus | L | 21 | (−62,−14,−6) | 4.27 | Parietal | ||||
| Superior Temporal Gyrus | R | 42 | (49,−21,7) | 4.51 | Angular Gyrus | L | 39 | (−44,−61,42) | 6.45 | |||||
| Superior Temporal Gyrus | R | 22 | (65,−16,6) | 3.87 | Occipital | |||||||||
| Parahippocampal Gyrus | L | 30 | (−26,−57,7) | 4.86 | Cuneus | L | 18 | (−14,−100,4) | 5.46 | |||||
| Cuneus | R | 19 | (19,−89,25) | 3.94 | ||||||||||
| Lingual Gyrus | R | 18 | (19,−78,09) | 5.04 | ||||||||||
| Rest > Forward Speech | ||||||||||||||
| Frontal | Frontal | Parietal | ||||||||||||
| Superior Frontal Gyrus | R | 9 | (−30,43,27) | −4.29 | Superior Frontal Gyrus | R | 6 | (13,7,42) | −5.39 | Postcentral Gyrus | L | 5 | (−30,−41,63) | −6.50 |
| Subcortical | ||||||||||||||
| Thalamus | L | (−10,−22,15) | −4.30 | |||||||||||
| Thalamus | R | (9,−22,16) | −5.47 | |||||||||||
| Backward Speech > Rest | ||||||||||||||
| None | Frontal | Frontal | ||||||||||||
| Insula | L | (−27,22,6) | 4.47 | Middle Frontal Gyrus | R | 46 | (30,10,22) | 5.21 | ||||||
| Middle Frontal Gyrus | L | 8 | (−42,2,31) | 4.72 | Inferior Frontal Gyrus | R | 44 | (57,5,22) | 4.35 | |||||
| Temporal | ||||||||||||||
| Superior Temporal Gyrus | R | 22 | (57,−18,2) | 4.89 | ||||||||||
| Superior Temporal Gyrus | R | 22 | (59,−5,−1) | 5.25 | ||||||||||
| Superior Temporal Gyrus | L | 22 | (−58,−21,2) | 6.49 | ||||||||||
| Transverse Temporal Gyrus | L | 41 | (−43,−14,7) | 4.58 | ||||||||||
| Middle Temporal Gyrus | L | 21 | (−58,−50,−5) | 6.40 | ||||||||||
| Rest > Backward Speech | ||||||||||||||
| None | None | Frontal | ||||||||||||
| Precentral Gyrus | L | 4 | (−17,−21,61) | 3.93 | ||||||||||
| Parietal | ||||||||||||||
| Postcentral Gyrus | R | 3 | (21,−33,59) | 4.11 | ||||||||||
| Paracentral Lobule | R | 4 | (2,−33,54) | 3.73 | ||||||||||
| Forward Speech > Backward Speech | ||||||||||||||
| Frontal | Temporal | Frontal | ||||||||||||
| Precentral Gyrus | R | 43 | (50,−4,13) | 3.61 | Superior Temporal Gyrus | R | 42 | (50,−20,11) | 3.47 | Insula | L | (−34,−1,6) | 4.05 | |
| Temporal | Superior Temporal Gyrus | R | 21 | (67,−18,4) | 3.44 | Middle Frontal Gyrus | L | 11 | (−22,44,−14) | 3.99 | ||||
| Superior Temporal Gyrus | R | 42 | (51,−28,11) | 3.17 | Middle Temporal Gyrus | R | 21 | (61,−10,−17) | 4.96 | Medial Frontal Gyrus | L | 32 | (−6,47,−9) | 4.25 |
| Superior Temporal Gyrus | L | 22 | (−50,−6,6) | 4.11 | Inferior Temporal Gyrus | R | 20 | (45,−1,−25) | 4.59 | Medial Frontal Gyrus | R | 32 | (10,45,−13) | 4.28 |
| Parahippocampal Gyrus | L | 30 | (−27,−57,7) | 3.45 | Anterior Cingulate Cortex | L | 32 | (−3,34,19) | 4.32 | |||||
| Parietal | Cingulate Gyrus | R | 32 | (1,6,34) | 4.33 | |||||||||
| Precuneus | L | 40 | (−22,−62,31) | 3.45 | Temporal | |||||||||
| Precuneus | R | 7 | (13,−66,35) | 3.97 | Superior Temporal Gyrus | L | 22 | (−47,−17,2) | 3.26 | |||||
| Paracentral Lobule | L | 7 | (−5,−32,46) | 3.93 | Parahippocampal Gyrus | R | 28 | (21,−13,−13) | 3.64 | |||||
| Precuneus | L | 7 | (−1,−57,46) | 4.10 | Parahippocampal Gyrus | R | 28 | (−14,−25,−9) | 3.24 | |||||
| Parietal | ||||||||||||||
| Precuneus | L | 7 | (−3,−41,43) | 4.21 | ||||||||||
| Angular Gyrus | L | 39 | (−42,−61,43) | 4.77 | ||||||||||
| Occipital | ||||||||||||||
| Cuneus | L | 18 | (−18,−88,27) | 4.78 | ||||||||||
| Cuneus | L | 17 | (−18,−97,3) | 4.00 | ||||||||||
| Cuneus | R | 18 | (10,−93,23) | 5.16 | ||||||||||
| Subcortical | ||||||||||||||
| Putamen | R | (18,−1,−5) | 3.72 | |||||||||||
| Putamen | L | (−18,10,10) | 3.25 | |||||||||||
| Backward Speech > Forward Speech | ||||||||||||||
| Frontal | Frontal | Frontal | ||||||||||||
| Middle Frontal Gyrus | L | 9 | (−29,43,27) | −3.69 | Precentral Gyrus | R | (50,3,35) | −3.74 | Postcentral Gyrus | R | 43 | (61,−6,15) | −4.11 | |
| Parietal | Temporal | |||||||||||||
| Subcortical | Postcentral Gyrus | L | (−15,−47,63) | −2.86 | Superior Temporal Gyrus | L | 21 | (−38,−9,−5) | −3.65 | |||||
| Cerebellum | R | (30,−48,−37) | −4.99 | Subcortical | ||||||||||
| Cerebellum | L | (−38,−68,−21) | −4.02 | Thalamus | L | (−7,−6,7) | −3.91 | |||||||
The peak t-value and Talairach coordinate is given for each region or Brodmann Area showing significant activity.