randomized controlled trial.pt.
(randomized or randomised).ab,ti.
placebo.ab,ti.
randomly.ab,ti.
trial.ab,ti.
groups.ab,ti.
dt.fs.
or/1–7
exp animals/
exp humans/
9 not (9 and 10)
8 not 11
exp clinical trial/
(clin$ adj3 trial$).tw.
((singl$ or doubl$ or trebl$ or tripl$) adj3 (blind$ or mask$)).tw.
placebo$.tw.
random$.tw.
exp experimental design/
exp control group/
18 or 19 or 16 or 13 or 17 or 15 or 14
angiogenes$.tw.
exp angiogenesis inhibitors/
exp angiogenic factor/
endothelial cell growth facto$.tw.
exp vasculotropin/
(macugen$ or pegaptanib$ or lucentis$ or rhufab$ or ranibizumab$ or bevacizumab$).tw.
(anti adj2 VEGF$).tw.
(endothelial adj2 growth adj2 factor$).tw.
exp angiogenesis inducing agents/
27 or 25 or 28 or 21 or 26 or 22 or 24 or 23 or 29
exp diabetic retinopathy/
exp macular edema cystoid/
exp macular degeneration/
(macula$ adj2 edema).tw.
(macula$ adj2 edema).tw.
DME.tw.
DMO.tw.
CME.tw.
CSME.tw.
(macula$ adj2 swell$).tw.
microaneurysm$.tw.
(dilat$ adj2 capillar$).tw.
35 or 33 or 32 or 39 or 40 or 36 or 41 or 42 or 38 or 34 or 37 or 31
30 and 43 and 20
from 44 keep 2, 9, 11–12, 15, 22–23, 27... 28
from 45 keep 1, 3, 5, 7, 9–10, 12... 15
from 46 keep 5, 7–9, 12–15 8
from 47 keep 1–3, 5–6 5