Figure 8. Small community in the CS consensus network highlights a dimerization interface.

Here we show a closeup view of the CS structure from Figure 7 and the network colored in magenta. Viewed on a single copy of the CS structure, the magenta community seems to be meaningless. However, when CS dimerization is considered, the magenta community shows its role as a key set of residues mitigating an inter-subunit coupling. Also of note is that the residue topology in the consensus network exactly mimics their minimum distance topology in the tertiary structure.