Table 2. Inhibition of enzymatic activities of porcine pancreatic group IB (pGIB) and human group IIA (hGIIA) PLA₂s by compounds C1 to C8 and their corresponding log P values.

Cpd	Log P *	IC50 (µM)
		hGIIAPLA2	pGIBPLA2
C1	3.81	5.0±0.7	>100
C2	5.59	10.0±1.5	>100
C3	2.88	5.0±1.2	>100
C4	4.57	6.5±1.8	>100
C5	3.91	2.5±0.5	>100
C6	5.59	3.0±0.2	>100
C7	3.64	35±1.8	>100
C8	7.13	0.62±0.15	>100

*: calculated using the Rekker's hydrophobic fragmental constants