Table 1. Sub-populations of the “Benefit Cohort Population.”.

Population Group	Subgroup	Definition
1. Individuals protected from acquiring infection (and subsequent disease)	a. Newborns	Babies born into MDA treated areas and whose entire lives are protected from potential LF infection and morbidity
	b. Other individuals protected from infection	Individuals who would have acquired infection but are protected because of interrupted transmission of LF resulting from MDA
2. Individuals infected with LF but protected from progression of disease	a. Subclinical disease	Patients with subclinical infection at the time of MDA who are protected from progression to clinical disease as a result of MDA
	b. Clinical disease	Individuals with clinical disease at the time of MDA who are either protected from worsening of their disease or actually undergo improvement as a result of MDA