Table 1.

Known RA SNP Associations

SNP	Locus	Candidate Gene	OR	Allele Frequency	References
rs3890745	1p36.2	TNFSF14	0.920	0.320	Raychaudhuri 2008
rs2240340a	1p36.13	PADI4	1.40	0.373	Suzuki 2003
rs2476601	1p13.2	PTPN22	1.750	0.100	Begovich 2004
rs11586238	1p13.1	CD2, IGSF2, CD58	1.120	0.227	Raychaudhuri 2009
rs7528684a	1q23.1	FCLR3	1.2	0.35	Kochi 2005
rs12746613	1q23.2	FCGR2A	1.100	0.124	Raychaudhuri 2009
rs3766379a	1q23.3	CD244	1.31	0.53	Suzuki 2008
rs10919563	1q31.3	PTPRC	0.900	0.132	Raychaudhuri 2009
rs13031237	2p16.1	REL	1.207	0.340	Gregersen 2009
rs934734	2p14	SPRED2	1.13	0.51	Stahl 2010
rs10865035	2q11.2	AFF3	1.140	0.460	Barton 2009
rs7574865	2q32.3	STAT4	1.320	0.180	Remmers 2007
rs1980422	2q33.2	CD28	1.100	0.238	Raychaudhuri 2009
rs3087243	2q33.2	CTLA4	1.136	0.560	Plenge 2005
rs13315591	3p14	PXK	1.13	0.08	Stahl 2010
rs874040	4p15	RBPJ	1.18	0.30	Stahl 2010
rs6822844	4q27	IL2/IL21	1.389	0.710	Zhernakova 2007
rs6859219	5q11	ANKRD55	0.85	0.22	Stahl 2010
rs26232	5q21	C5orf13	0.93	0.32	Stahl 2010
rs2395175 (and others)	6p21.32	MHC	1.000	0.021	Gregersen 1987
rs548234	6q21	PRDM1	1.100	0.322	Raychaudhuri 2009
rs10499194	6q23.3	TNFAIP3 (a)	1.220	0.220	Plenge 2007a
rs6920220	6q23.3	TNFAIP3 (b)	1.333	0.610	Thomson 2007
rs5029937	6q23.3	TNFAIP3 (c)	1.34	0.04	Orozco 2009
rs394581	6q25.3	TAGAP	0.930	0.286	Raychaudhuri 2009
rs3093023	6q27	CCR6	1.11	0.43	Stahl 2010
rs10488631	7q32	IRF5	1.25	0.10	Stahl 2010
rs2736340	8p23.1	BLK	1.122	0.243	Gregersen 2009
rs2812378	9p13.3	CCL21	1.100	0.355	Raychaudhuri 2008
rs951005	9p13.3	CCL21	0.87	0.15	Stahl 2010
rs3761847	9q33.1	TRAF1	1.100	0.440	Plenge 2007b; Kurreeman 2007
rs2104286	10p15.1	IL2RA	0.92	0.28	Thomson 2007; Kurreeman 2009
rs706778	10p15.1	IL2RA	1.11	0.40	Stahl 2010
rs4750316	10p15.1	PRKCQ	0.910	0.183	Raychaudhuri 2008; Barton 2008
rs540386	11p12	RAG1, TRAF6	0.920	0.144	Raychaudhuri 2009
rs1678542	12q13.3	KIF5A	0.890	0.351	Barton 2008; Raychaudhuri 2008
rs4810485	20q13.12	CD40	0.910	0.231	Raychaudhuri 2008
rs3218253	22q12.3	IL2RB	1.110	0.730	Barton 2008